Events

• January 4 - Christopher Columbus leaves the New World, ending his first journey.
• March 15 - Christopher Columbus returns to Spain after his first trip to the Americas.
• July 28 - Great fire in Moscow
• November 19 - Christopher Columbus becomes the first European to go ashore on an island he only saw for the first time the day before. He names it San Juan Bautista (later renamed Puerto Rico).

Births

• October 14 - Shimazu Tadayoshi, Japanese daimyo
• Bartolommeo Bandinelli
• Paracelsus

Deaths

• June 14, Ermolao Barbaro
• August 19 - Frederick III, Holy Roman Emperor
• Constantine Lascaris