AFB is a TLA that may stand for:

• Absolute fairness bound
• Acid-fast bacilli
• Air Force base
• Akademie für Bioenergetik (afb.li)
• American Farm Bureau
• American foulbrood (honeybee disease)
• American Foundation for the Blind (afb.org)
• Amt für Berufsbildung (Lucerne)
• Anaerobic fluidized bed
• Anti-friction bearing
• Arbeitsstelle Friedensforschung Bonn
• Assault Float Bridge (US Army)
• Association for Biometrics (afb.org.uk)
• Association Française des Banques (afb.fr)
• Atmospheric fluidized bed

• SIL code for spoken Gulf Arabic