Antiochus I Theos was king of the small Middle East kingdom of Kommagene (69 - 40 BC).

The son of king Mithradates Callinicus and a Seleucid princess Laodice, Antiochus is famous for founding the impressive sanctuary of Nemrud Dagi. Despite his efforts, his reign ended with Kommagene submitting to the Roman empire, and becoming a client-state under Augustus.