Antonio Guzmán Fernández (1911–July 4, 1982) was the President of the Dominican Republic from 1978 to 1982.

Silvestre Antonio Guzmán Fernández was born in the town of La Vega on February 12, 1911. He studied in the primary and secondary schools of La Vega.

He worked in the fruit exportation business until 1963, when he became Secretary of Agriculture in the government of Juan Bosch. He lost this position when Bosch was overthrown in a coup d'état later in 1963. In May 1966 he was the vice-presidential candidate for the Dominican Revolutionary Party (PRD), with Bosch as the candidate for president. The elections were won, however, by Joaquín Balaguer.

The PRD won the election in 1978, beating incumbent Balaguer, who had been president for 12 years. Antonio Guzmán occupied the presidency and Jacobo Majluta Azar the vice-presidency.

Guzmán's political base was in the agricultural and agroindustrial sectors. He was popular among the middle and lower class, for his rural development and employment programmes.

Guzmán committed suicide on July 4, 1982, while still president; Jacobo Majluta was appointed president for a month, to complete Guzmán's term.