Charles Robert Harrison (July 3, 1868-February 7, 1946) was a Canadian politician. He represented the riding of Nipissing in the Canadian House of Commons from 1917 to 1921. He was a Conservative member of Robert Borden's Unionist caucus.

Harrison, who was born in Frodingham , England, was a train conductor before entering politics.

He served only a single term, and was defeated by Edmond Lapierre in the 1921 election.