Dorothy Walker Bush (July 1, 1901 - November 19, 1992) was the mother of the 41st President of the United States, George H. W. Bush, and the grandmother of the 43rd president, George W. Bush. She was born near Walker's Point, in York County, Maine.

Walker married Prescott Sheldon Bush on August 6, 1921, in Kennebunkport, Maine. They had five children: George H. W. Bush (named after Dorothy's father, George Herbert Walker), Prescott Bush, Jr., Jonathan Bush, William Bush, and Nancy Bush.

Dorothy Walker died in Greenwich, Connecticut, on November 19, 1992.