The Fourche La Fave River (foosh luh FAIV) is a tributary of the Arkansas River, approximately 140 mi (225 km) long, in western Arkansas in the United States. It drains part of the northern Ouachita Mountains west of Little Rock.

It rises in southern Scott County south of Waldron and flows ENE through the Ouachita National Forest, along the southern side of the Dutch Creek Mountain ridge, then along the north side of the Fourche Mountain ridge. It flows past Perryville and joins the Arkansas from the west approximately 25 mi (40 km) northwest of Little Rock. It is impounded by the Nimrod Dam at Fourche Junction to form Nimrod Lake for flood control. It is joined by the South Fourche La Fave River west of Perryville.