Francis II (February 27 1572 – October 14 1632), was Duke of Lorraine briefly in 1624, quickly abdicating in favor of his son. He married Christina of Salm and had the following issue:

• Henry (1602-1611)
• Duke Charles III of Lorraine (1604-1675)
• Henrietta (1605-1660), married Louis of Guise, prince of Lixheim
• Duke Nicholas II of Lorraine (1609-1670)
• Margaret (1615-1672), married Gaston, Duke of Orleans
• Christina (1621-1622)

See also: Dukes of Lorraine family tree