Frank D. Celebrezze I (died 1953) was the brother of Johnson cabinet member and federal appeals court Judge Anthony Celebrezze.

In the 1930s, Celebrezze served as a Cleveland, Ohio, municipal judge. Later, he was director of safety under Cleveland mayors Frank J. Lausche and Thomas Burke . Then, Celebrezze served as an assistant prosecutor in the Cuyahoga County, Ohio, prosecutor's office.

His other relatives include nephews gubernatorial candidate Anthony J. Celebrezze Jr., Ohio Chief Justice Frank Celebrezze, Ohio Supreme Court Judge James Celebrezze; Ohio appeals court Judge Frank D. Celebrezze Jr.; and Anthony J. Celebrezze III.