Frederick George Payne (July 24, 1904 - June 15, 1978) was a Republican politician from the U.S. state of Maine. He was born in Lewiston, Maine.

He was mayor of Augusta, Maine before being elected Governor in 1948. He was reelected as Governor in 1950 and in 1952 was elected to the U.S. Senate, but was defeated for reelection in 1958 by Democrat Ed Muskie.