Isandlwana is an isolated hill in the KwaZulu-Natal province of South Africa.

On January 22, 1879, Isandlwana was the site of the Battle of Isandlwana, where over 20,000 Zulu warriors routed a contingent of British soldiers in the first engagement of the Anglo-Zulu War. Almost the entire column of about 1,200 British soldiers was killed, and the regimental colours were lost.