Sir Leoline Jenkins (1625 - 1 September 1685) was a lawyer and diplomat, originally from Cowbridge in south Wales.

As Principal of Jesus College, Oxford from 1661-1673, he was responsible for much construction work, including the college library. The position was one of several rewards he received from King Charles II of England for his loyalty to the Royalist cause during the English Civil War; he was also created a judge.

Jenkins was made a privy councilor in February 1680. He served as Secretary of State for the Northern Department from April 26, 1680 to February 2, 1681 and Secretary of State for the Southern Department from February 2, 1681 to April 14, 1684. His major achievements include authoring the Statute of frauds (29 Car. II c. 3) and the Statute of distributions (22 & 23 Car. II, c. 10), dealing with the inheritance of personal property.

He is regarded as the founder of the eminent Cowbridge Grammar School , renowned for its academic standards.