• Mark the Evangelist (43–63)
• Anianus (61–82)
• Avilius (83–95)
• Kedron (96–106)
• Primus (106–118)
• Justus (118–129)
• Eumenes (131–141)
• Mark II of Alexandria (142–152)
• Celadion (152–166)
• Agrippinus (167–178)
• Julian (178–189)
• Demetrius (189–232)
• Heraclas (232–248)
• Dionysius (248–264)
• Maximus (265–282)
• Theonas (282–300)
• Peter I (300–311)
• Achillas (312–313)
• Alexander I (313–328)
• Athanasius I (328–339)
• Gregory of Cappadocia (339–346) (most in the Coptic Church deny his papacy and say Athanasius was the true patriarch)
• Athanasius I (restored) (346–373)
• Peter II (373–380)
• Timothy I (380–385)
• Theophilus I (385–412)
• Cyril I (412–444)
• Dioscorus I (444–451)

In 451 the Coptic Church split from the Eastern Orthodox Church of Alexandria. For later Patriarchs see List of Orthodox Patriarchs of Alexandria and List of Coptic Popes.