Louis Alfred "Pinky" Clarke (November 23, 1901 - February 24, 1977) was an American athlete, winner of hold medal in 4x100 m relay at the 1924 Summer Olympics.

Born in Statesville, North Carolina, Louis Clarke won, as a Johns Hopkins University student the NCAA 100 yd championships in 1923.

At the Paris Olympics, Clarke, ran the second leg in the American 4x100 m relay team, which won the gold medal in a new world record of 41.0.

Louis Clarke died in Fishkill, New York aged 75.