Lú Mùzhēn (卢慕贞) (1867 - 1952) was the first wife of Chinese revolutionary leader and first President of the Republic of China Sun Yat-sen.

A fellow villager, she married Sun when he was 19 and bore him a son, Sun Ke, and two daughters, Sun Yan and Sun Wan . But due mainly to her bound feet, she rarely accompanied him on his revolutionary campaigns. She moved to Macau after Sun divorced her in 1915 to marry Soong Ching-ling.