Merenre Antyemsaf I (2283 - 2278 BC ) was the fourth king of the Sixth dynasty of Egypt.

Merenre may have served as coregent with his father Pepi I Meryre before ruling in his own right. He shared his father's fascination with Nubia and continued to explore deep into the region. He also began a process of royal consolidation, appointing Uni as the first governor of all of Upper Egypt and expanding the power of several other governors. He probably died at an early age.