Mount Seir is the mountainous region allotted to the descendants of Esau, the Edomites. Mount Seir is specifically noted as the place that Esau made his home (Genesis 36:8; Joshua 24:4). It was named for Seir, the Horite, whose sons inhabited the land (Genesis 36:20). The children of Esau battled against the Horites and destroyed them (Deut. 2:12).