Paeonius (or Paionios) of Mende in Thrace was a Greek sculptor of the late 5th century BC. The only work that can be definitely attributed to him is the statue of Nike (circa 420 BC) discovered at Olympia. According to the inscription on the base, it was dedicated by the people of Messenia and Naupactus after a victory in an unnamed conflict, possibly the battle of Sphacteria.

Paeonius also won the commission to decorate the acroteria of the Temple of Zeus at Olympia (about 430 - 420 BC), Pausanias was probably wrong in claiming that he worked on the sculptures for the pediments of the temple.

The Nike of Paeonius featured as part of the design of the medals of the 2004 Summer Olympics in Athens.