Quainton railway station at Quainton in Buckinghamshire, England was the northern terminus of the Wotton (later Brill) Tramway. Originally opened in 1871, the tramway was one of the first 'light railways' opened under new legislation brought in to support local lines. Later subsumed onto the Metropolitan Railway's northern extensions, there were plans to extend the few miles from Brill to Oxford. The line to Brill was closed in 1935, shortly after nationalisation of London Underground.

Quainton Road station still remains as the headquarters of the Buckinghamshire Railway Heritage Centre. There are no regular train services, although special services operate from Aylesbury to link with events at the Heritage Centre.

The original line to Verney Junction has been closed and lifted, but the old Great Central main line remains, albeit singled, as far as the point where it crossed the Oxford and Cambridge cross country line. Here the construction of Calvert Curve permits onward freight running past Quainton Road towards Bletchley and Cambridge.