Several notable individuals have been named William Paterson:

• William Paterson (banker) (1658-1719), Scottish trader, a founder of the Bank of England, deviser of the Darién scheme
• William Paterson (jurist) (1745-1806), American statesman, signed US Constitution
• William Paterson (governor) (1755-1810), early lieutenant governor of Tasmania
• William Paterson (Canadian politician) (1839-1914), Canadian Member of Parliament
• William A. Paterson (1838-1921), US Auto manufacturer

In addition, the name may refer to:

• William Paterson University, public university located in Wayne, New Jersey

See also:

• William Patterson, a 19th century US politician.