The Zaikonospassky monastery (Заиконоспасский монастырь in Russian) is a male monastery in Moscow.

It was founded in 1600 by Boris Godunov. Between the late 17th - early 19th centuries, the Zaikonospassky monastery was one of the enlightenment centers of Russia. In 1687-1814, it was home to the famous Slavic Greek Latin Academy . Today's architectural ensemble of the monastery includes the Spassky Cathedral (built in 1660-1661; re-constructed in 1717-1720 and 1742), chambers of the 17th century and former school building (1822).

The Zaikonospassky monastery was abolished after the October Revolution. There is a memorial plaque in honor of Mikhail Lomonosov, who was once a student at this monastery.